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Merck and Eisai Report Welireg Plus Lenvatinib Hits PFS Goal in Previously Treated Advanced Kidney Cancer

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Merck and Eisai announced that the combination of Welireg (belzutifan) and lenvatinib met its dual primary endpoint in patients with advanced clear cell renal cell carcinoma who had previously received a PD-1 or PD-L1 inhibitor, delivering a statistically significant and clinically meaningful improvement in progression-free survival. The combination was tested against cabozantinib, the current standard of care in that setting, and reduced the risk of disease progression or death by 30%, with a median PFS of 14.8 months compared to 10.7 months for cabozantinib.

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  1. MarketsdayMerck’s Welireg Plus Lenvatinib Meets PFS Goal in Advanced Kidney Cancer – November 13, 2026 🔹 Merck $MRK announced that the combination of Welireg (belzutifan) and lenvatinib achieved a statistically significant and clinically meaningful improvement in progression-free survival (PFS). 🔹 The combination met the dual primary endpoint in patients with advanced clear cell renal cell carcinoma (ccRCC). 🔹 The trial involved patients previously treated with a PD-1 or PD-L1 inhibitor. \#Merck #MRK #Welireg #Lenvatinib #Oncology #CancerResearch #PharmaStocks
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