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Teva Drops Phase 2 Trial of Emrusolmin for Multiple System Atrophy After Futility Analysis

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Teva Pharmaceutical Industries is discontinuing its Phase 2 TOPAS-MSA study of emrusolmin, also known as TEV-'286, a drug candidate targeting multiple system atrophy, a rare and fatal neurodegenerative disorder. The decision follows an interim futility analysis that indicated the mid-stage trial was unlikely to meet its primary endpoints.

Shares of Teva fell approximately 3.3% in premarket trading on the news, reflecting investor disappointment over the setback to the company's neuroscience pipeline.

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Sources

  1. BioStocks$TEVA to Discontinue Phase 2 TOPAS-MSA Study of emrusolmin (TEV-‘286) Following Interim Futility Analysis
  2. Seeking AlphaTeva discontinues Phase 2 study of Emrusolmin in multiple system atrophy
  3. ReutersTeva to discontinue mid-stage neurodegenerative disorder study
  4. OpenOutcrier$DRUG (-45.8% pre) FDA places Bright Minds Biosciences BMB-101 trial on partial hold
  5. TheflynewsTeva to discontinue TOPAS-MSA study $TEVA